Products

TOTAPOL

TOTAPOL is a patent-pending, highly-efficient, biradical polarization agent which contains two TEMPO radicals separated by a covalent linkage. This high-performance biradical is water soluble and is compatible with salt solutions commonly used in the study of nucleic acids and proteins. TOTAPOL is now available for purchase in 100mg and 1g quantities (email or use our contact page for a quotation).

When compared with other polarization agents TOTAPOL has distinct advantages:

+ TOTAPOL produces much higher enhancement values under certain operating conditions. When compared to the monoradical TEMPO, TOTAPOL produces over four times the polarization at four times lower electron concentration.

+ TOTAPOL is effective in much smaller quantities when compared to other radicals. The proximity of the two radicals in the biradical ensures polarization transfer even at low concentrations. This is especially advantageous in dissolution experiments or when a sample needs to be washed several times before it is analyzed.

+ TOTAPOL can be used with any brand of DNP-NMR spectrometer or suitably equipped MRI machine.

BDPAqua

BDPAqua is a patented, highly-efficient, narrow-line polarization agent. This BDPA-based molecule has been shown to perform solid-effect, solid-state Overhauser effect, and cross-effect polarizations (when paired with trityl for direct 13C polarization).BDPAqua, also known as SA-BDPA is now available for purchase in 100mg and 1g quantities (email or use our contact page for a quotation).

BDPAqua is sold in a number of configurations:

+ BDPAqua Na+ The sodium-salt form of BDPAqua is highly soluble in both water and glycerol-water media.

+ BDPAqua H+ This acidic form of the molecule is soluble in neat pyruvic acid for use in dissolution DNP experiments.

BDPA

The original! This unfunctionalized, stable free radical is available for purchase in 100mg and 1g quantities (email or use our contact page for a quotation). Note: this is the pure compound, not the co-crystal with benzene. Useful in both EPR and DNP spectroscopy. Recently used in solid-state Overhauser Effect experiments.

Nitroxide monoradicals

A variety of nitroxide monoradicals are available for purchase.

+ TEMPOL / 4-hydroxy TEMPO 
+ TEMPONE / 4-oxo TEMPO 
+ 4-acetamido TEMPO 
+ TEMPO  

For a limited time we are offering a promotional discount for our early customers. If you would like more information about TOTAPOL or would like to request a quotation please use our contact page.